This is not good news.
...ADE may not be occurring with the original Covid strain, but rather, ADE among the “fully vaccinated” is particular to the Delta variant. This would explain everything we have been seeing for the past six weeks, and now we have the science to prove it....
Want the long form of that? OK!!
“Antibody dependent enhancement (ADE) of infection is a safety concern for vaccine strategies. In a recent publication, Li et al. (Cell 184 :1-17, 2021) have reported that infection-enhancing antibodies directed against the N-terminal domain (NTD) of the SARS-CoV-2 spike protein facilitate virus infection in vitro, but not in vivo. However, this study was performed with the original Wuhan/D614G strain. Since the Covid-19 pandemic is now dominated with Delta variants, we analyzed the interaction of facilitating antibodies with the NTD of these variants. Using molecular modelling approaches, we show that enhancing antibodies have a higher affinity for Delta variants than for Wuhan/D614G NTDs. We show that enhancing antibodies reinforce the binding of the spike trimer to the host cell membrane by clamping the NTD to lipid raft microdomains. This stabilizing mechanism may facilitate the conformational change that induces the demasking of the receptor binding domain. As the NTD is also targeted by neutralizing antibodies, our data suggest that the balance between neutralizing and facilitating antibodies in vaccinated individuals is in favor of neutralization for the original Wuhan/D614G strain. However, in the case of the Delta variant, neutralizing antibodies have a decreased affinity for the spike protein, whereas facilitating antibodies display a strikingly increased affinity. Thus, ADE may be a concern for people receiving vaccines based on the original Wuhan strain spike sequence (either mRNA or viral vectors). Under these circumstances, second generation vaccines with spike protein formulations lacking structurally-conserved ADE-related epitopes should be considered.You do NOT want ADE.
Therefore, you should stay away from The Vax and simply start a preventive-dose regimen of Ivermectin.
9 comments:
"Under these circumstances, second generation vaccines with spike protein formulations lacking structurally-conserved ADE-related epitopes should be considered."
yyyeeeeaaahhhhhh....noooooooooooooooo. Second generation...and third, and fourth, and nine hundred and sixty-third generation. Just, NO.
Thank you Sir. For those of your readers who are unaware, I recommend https://covid19criticalcare.com/ and https://aapsonline.org/ for further information.
Great, but Ivermectin can't be bought over the counter and most doctors refuse to prescribe it. It's a not so subtle form of coercion to force people to get the shot.
American Frontline Doctors can prescribe Ivermectin and Hydroxy, etc., and it is sent to your home. So can some of these other medical organizations. Also to get Ivermectin go to animal feed stores. Ivermectin is given to humans and animals as an anti-viral. The 1% injectable is able to be taken in any liquid, you don't inject it.
I had Covid delta last week. I had very light symptoms. It came and went. I have Ivermectin and zinc on hand, but this is for my elderly father should he get sick.
Natural immunity and vitamin d will be sufficient to fight any Coronavirus if you are healthy. You are not healthy if you've been vaxxed with the death jab.
Do not be afraid. Just be prepared.
You can buy Ivermectin over the counter at any feed store.
What Fred said. Any ranch and feed store will have Ivermectin reavailable.
YMMV
https://market-ticker.org/akcs-www?post=243281
Yah--I've heard that the now-recc'd Ivermectin dosage is 200% of the older recc. Delta rips through Ivermectin like Kleenex
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